HCID 68296408, compound → HCID 68296409, compound

HRID 631881Notes

Reaction equation

HRID 631881 reaction equation
[CH2:1]([N:8]1[C:12]([C:13]2[C:18]([N+:19]([O-])=O)=[CH:17][CH:16]=[CH:15][C:14]=2[O:22][CH3:23])=[N:11][N:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>C(O)C.[Pt]>[CH2:1]([N:8]1[C:12]([C:13]2[C:14]([O:22][CH3:23])=[CH:15][CH:16]=[CH:17][C:18]=2[NH2:19])=[N:11][N:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 68296408HCID 68296408, compound2×HCID 178418361HCID 178418361, compound

Product 1

HCID 68296409HCID 68296409, compoundYield 94.8%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 702EthanolSolvent

Procedure

1-Benzyl-5-(2-methoxy-6-nitrophenyl)-1H-tetrazole (Intermediate 14, 0.14 g) was dissolved in ethanol (5 mL) under a nitrogen atmosphere. Platinum on carbon (10%, 0.01 g) was added and the nitrogen atmosphere was replaced by hydrogen. The mixture was stirred for 18 hours and then filtered through celite. The filtrate was evaporated to dryness to give the title compound as a brown gum (0.12 g).

Workup

  1. filtrationfiltered through celite
  2. customThe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-31c0d21fadf54400adfb63c136180632
Source dataset
uspto-grants-2016_04
Patent number
US09321740B2

Reaction notes

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