反应详情

温度

80 °C

16 g (43.3 mmol) of 2-(3-bromophenyl)-4,6-diphenylpyrimidine 14 and 19.3 g (48 mmol) of 7-borono12,12-dimethyl-10-phenyl-10,12-dihydro-10-azaindeno[2,1-b]fluorene 13 are dissolved in 80 ml of toluene and degassed. 281 ml of a degassed 2M K2CO3 and 2.5 g (2.2 mmol) of Pd(OAc)2 are added. The reaction mixture is subsequently stirred for 48 h at 80° C. under a protective-gas atmosphere. Additional toluene is added to the cooled solution, which is washed a number of times with water, dried and evaporated. The product is purified by column chromatography on silica gel with toluene/heptane (1:2). The purity is 99.9%. Yield: 22 g (31 mmol), 77% of theory.

1. customdegassed
2. washis washed a number of times with water
3. customdried
4. customevaporated
5. customThe product is purified by column chromatography on silica gel with toluene/heptane (1:2)