反应详情

温度

100 °C

In a 300 ml flask equipped with a stirrer, a condenser and a calcium chloride dryer tube were charged 13.2 g of octadecanthiol, 14.3 g of 11-bromoundedanamide, 1.7 g of potassium iodide, 20.7 g of potassium carbonate and 100 ml of DMAc, and the mixture was stirred at 100° C. for 5 hours. After cooling the reaction mixture to room temperature, the reaction mixture was poured into ice-water and precipitated crystals were collected by filtration under reduced pressure, and washed with distilled water. The resulting crystals were recrystallized from IPA to obtain 16.4 g of the title compound. Melting point: 108° C.

1. customIn a 300 ml flask equipped with a stirrer, a condenser and a calcium chloride dryer tube
2. temperatureAfter cooling the reaction mixture to room temperature
3. customprecipitated crystals
4. filtrationwere collected by filtration under reduced pressure
5. washwashed with distilled water
6. customThe resulting crystals were recrystallized from IPA