反应详情

The procedure of example 79c was followed, using 3-phenylpropionic acid and serinol. At the end of the reaction, the DMF was evaporated and CH2Cl2 was added to the residue. The white crystalline material was collected and gave pure N-(2-hydroxy-1-hydroxymethyl-ethyl)-3-phenyl-propionamide as a white solid (56%, MS: m/e=224.2 (M+H+)).

1. customAt the end of the reaction
2. customthe DMF was evaporated
3. additionCH2Cl2 was added to the residue
4. customThe white crystalline material was collected