反应详情

Ethyl chloroformate (1.2 eq) was added to 2-(1,3-dioxolan-2-yl)-4-methoxyphenylamine (1eq) and triethyl amine (1.2 eq) in THF at 0° C. The reaction was completed instantaneously. The mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine and dried and concentrated to give N-(2-(1,3-dioxolan-2-yl)-4-methoxyphenyl)ethoxycarboxamide as a yellow solid in quantitative yield.

1. concentrationThe mixture was concentrated
2. custompartitioned between ethyl acetate and water
3. washThe organic layer was washed with brine
4. customdried
5. concentrationconcentrated