HCID 59256646, compound → HCID 136352897, compound

HRID 640796Notes

Reaction equation

HRID 640796 reaction equation
C([O:8][C:9]1[C:10]([Cl:24])=[CH:11][C:12]([Cl:23])=[C:13]2[C:18]=1[N:17]=[C:16]([CH2:19][N:20]([CH3:22])[CH3:21])[CH:15]=[N:14]2)C1C=CC=CC=1>Cl>[ClH:23].[Cl:24][C:10]1[CH:11]=[C:12]([Cl:23])[C:13]2[N:14]=[CH:15][C:16]([CH2:19][N:20]([CH3:21])[CH3:22])=[N:17][C:18]=2[C:9]=1[OH:8]

Participants

3

Reactant 1

HCID 59256646HCID 59256646, compound

Product 1

HCID 136352897HCID 136352897, compoundYield 166.7%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of (8-benzyloxy-5,7-dichloro-quinoxalin-2-ylmethyl)dimethylamine (38 mg, 0.105 mmol) in conc HCl (2 mL) was stirred at room temperature for 16 h. The orange solution was concentrated to dryness and the remaining residue was washed with diethyl ether (2 ml×3) to give the desired product as a light yellow solid (27 mg, 83%).

Workup

  1. concentrationThe orange solution was concentrated to dryness
  2. washthe remaining residue was washed with diethyl ether (2 ml×3)

Sources & evidence

ORD record
ord-05af723e6c1d47d7a22e58b387018a4f
Source dataset
uspto-grants-2010_04
Patent number
US07692011B2

Reaction notes

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