Benzyl Bromide → 2-Benzyloxy-6-but-3-enyloxy-N,N-dimethylbenzamide

HRID 643882Notes

Reaction equation

HRID 643882 reaction equation
[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][CH:17]=[C:16]([OH:20])[C:10]=1[C:11]([N:13]([CH3:15])[CH3:14])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:22][CH2:23][CH:24]=[CH2:25].C(Br)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH2:25][CH2:24][CH:23]=[CH2:22])[C:10]=1[C:11]([N:13]([CH3:15])[CH3:14])=[O:12])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 21241Homoallyl bromideHCID 667505692-benzyloxy-6-hydroxy-N,N-dimethylbenzamide

Product 1

HCID 667504902-Benzyloxy-6-but-3-enyloxy-N,N-dimethylbenzamide

Procedure

The title compound is prepared analogously to Example 1, step B, from 2-benzyloxy-6-hydroxy-N,N-dimethylbenzamide (Example 13, step C) except using 4-bromo-but-1-ene to replace benzyl bromide.

Sources & evidence

ORD record
ord-f4be6efa375f492d935c393111c62b28
Source dataset
uspto-grants-2010_04
Patent number
US07700633B2

Reaction notes

Loading…