反应详情

To a suspension of 510 mg of 8-(cyclohexylmethoxy)-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid in dichloromethane were added 0.30 ml of oxalyl dichloride and one drop of DMF under ice-cooling, followed by stirring at room temperature for 30 minutes, and the solvent was evaporated under reduced pressure to obtain 603 mg of 8-(cyclohexylmethoxy)-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid chloride hydrochloride.

1. temperaturecooling
2. customthe solvent was evaporated under reduced pressure