Ammonium formate → HCID 58662440, compound

HRID 644815Notes

Reaction equation

HRID 644815 reaction equation
C(OC([N:11]1[C:20]2[C:15](=[CH:16][C:17]([CH3:22])=[N:18][C:19]=2[CH3:21])[C:14](=[O:23])[CH2:13][CH:12]1[CH2:24][CH3:25])=O)C1C=CC=CC=1.C([O-])=O.[NH4+]>CO.[Pd]>[CH2:24]([CH:12]1[CH2:13][C:14](=[O:23])[C:15]2[C:20](=[C:19]([CH3:21])[N:18]=[C:17]([CH3:22])[CH:16]=2)[NH:11]1)[CH3:25]

Participants

5

Reactant 2

HCID 2723923Ammonium formateHCID 58662444HCID 58662444, compound

Product 1

HCID 58662440HCID 58662440, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

This compound can be obtained by reacting a solution of 2-ethyl-6,8-dimethyl-4-oxo-3,4-dihydro-2H-[1,7]naphthyridine-1-carboxylic acid benzyl ester in methanol, under nitrogen atmosphere, with ammonium formate (2.5 eqv) and 10% Pd—C (50% water wet), at about 40° C. for a time period of about 1 h, followed by a typical workup.

Workup

  1. customThis compound can be obtained
  2. customat about 40° C.
  3. customfor a time period of about 1 h

Sources & evidence

ORD record
ord-d523029be6f449e88091244dabee8b7f
Source dataset
uspto-grants-2010_04
Patent number
US07700774B2

Reaction notes

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