反应详情

To a solution of (1-acetyl-4-phenylpiperidin-4-ylmethyl)carbamic acid tert-butyl ester in ether is added 4 N HCl in 1,4-dioxane. The reaction mixture is stirred at room temperature for 1 h, and concentrated in vacuo. The resulting solid is washed with ether to give the title compound, which is directly used for the next reaction without further purification.

1. concentrationconcentrated in vacuo
2. washThe resulting solid is washed with ether