Hydrochloric Acid → HCID 68706690, compound

HRID 645487Notes

Reaction equation

HRID 645487 reaction equation
C(OC(=O)[NH:7][CH2:8][C:9]1([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:14][CH2:13][N:12]([C:15](=[O:17])[CH3:16])[CH2:11][CH2:10]1)(C)(C)C.[ClH:25]>CCOCC.O1CCOCC1>[ClH:25].[NH2:7][CH2:8][C:9]1([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:10][CH2:11][N:12]([C:15](=[O:17])[CH3:16])[CH2:13][CH2:14]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 68706126HCID 68706126, compound

Product 1

HCID 68706690HCID 68706690, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 312751,4-DioxaneSolvent

Procedure

To a solution of (1-acetyl-4-phenylpiperidin-4-ylmethyl)carbamic acid tert-butyl ester in ether is added 4 N HCl in 1,4-dioxane. The reaction mixture is stirred at room temperature for 1 h, and concentrated in vacuo. The resulting solid is washed with ether to give the title compound, which is directly used for the next reaction without further purification.

Workup

  1. concentrationconcentrated in vacuo
  2. washThe resulting solid is washed with ether

Sources & evidence

ORD record
ord-eb968db4ea084ac79dd1ef5970d10c29
Source dataset
uspto-grants-2010_04
Patent number
US07704996B2

Reaction notes

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