反应详情

To a solution of crude methyl-(6-methyl-1H-indol-3-ylmethyl)-amine (87 mg) in acetonitrile (1 ml) was added diisopropylethyl amine (0.25 ml) and 4-nitrophenyl formate (90 mg) and stirring was continued for 3 h. The mixture was diluted with methanol and acetic acid evaporated and the residue was chromatographed on silica using n-heptane/AcOEt (1:1) to give N-methyl-N-(6-methyl-1H-indol-3-ylmethyl)-formamide as a colorless oil. MS: 202.9 ([M]+).

1. customevaporated
2. customthe residue was chromatographed on silica