Acetyl chloride → HCID 20278223, compound

HRID 647530Notes

Reaction equation

HRID 647530 reaction equation
[C:1]1([CH:7]2[S:20][C:14]3([CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]2=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(N(CC)CC)C.[C:28](Cl)(=[O:30])[CH3:29]>C(Cl)(Cl)Cl>[C:28]([N:17]1[CH2:16][CH2:15][C:14]2([C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[CH:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[S:20]2)[CH2:19][CH2:18]1)(=[O:30])[CH3:29]

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 12694098HCID 12694098, compound

Product 1

HCID 20278223HCID 20278223, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

A cold stirred solution of 1,3-dihydro-3-phenylspiro[benzo(c)thiophene-1,4'-piperidine], Example 4, and triethylamine in 50 ml of chloroform is treated dropwise with a solution of acetyl chloride in chloroform to provide 1'-acetyl-1,3-dihydro-3-phenylspiro[benzo(c)thiophene-1,4'-piperidine].

Sources & evidence

ORD record
ord-3a5bc2a2949a494d9f0691b93c3105a1
Source dataset
uspto-grants-1983_10
Patent number
US04409229

Reaction notes

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