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HRID647749

反应详情

EQUATION

反应方程式

HRID 647749 的结构方程式

REACTANTS

反应物

3
结构：Cl.ClCc1ccccn1
HCID23392

2-(Chloromethyl)pyridine hydrochloride

C6H7Cl2N

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CCC1(CO)CCC2(CCOCC2)O1
HCID13237164

(2-Ethyl-1,8-dioxaspiro[4.5]decan-2-yl)methanol

C11H20O3

PRODUCTS

生成物

1
结构：CCC1(COCc2ccccn2)CCC2(CCOCC2)O1
HCID13237166

2-{[(2-Ethyl-1,8-dioxaspiro[4.5]decan-2-yl)methoxy]methyl}pyridine

C17H25NO3

收率 62.5%

PROCEDURE

实验过程

Following procedures similar to Embodiments XVII-XIX, 1.10 g of 2-ethyl-1,8-dioxaspiro[4.5]decane-2-methanol was treated with 1.35 g of 2-picolinyl chloride hydrochloride in the presence of sodium hydride to yield 1.00 g of the desired product as pale yellow liquid.