反应详情

Each of 3-(2-fluoro-4-trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione and 3-(4-trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione, prepared by the procedure of Example 77, is reacted with m-benzoylbenzaldehyde and potassium cyanide using the procedure of Example 71 to yield the m-benzoyl α-cyanobenzyl ester of N-(2-fluoro-4-trifluoromethylphenyl)valin and the m-benzoyl-α-cyanobenzyl ester of N-(4-trifluoromethylphenyl)valine.