Triethylamine → HCID 123220109, compound

HRID 648760Notes

Reaction equation

HRID 648760 reaction equation
[O:1]1[CH2:5][CH2:4][NH:3][C:2]1=[O:6].C(N(CC)CC)C.[CH3:14][SiH:15]([CH3:17])Cl>O1CCCC1>[CH3:14][SiH:15]([CH3:17])[N:3]1[CH2:4][CH2:5][O:1][C:2]1=[O:6]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 66108ChlorodimethylsilaneHCID 739492-Oxazolidinone

Product 1

HCID 123220109HCID 123220109, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A 3-dimethylsilyl-2-oxazolidinone was prepared in accordance with the following procedure. To a stirred mixture of 34.8 grams of 2-oxazolidinone and 40.4 grams of triethylamine in 600 ml of a tetrahydrofuran solvent, 45 ml of dimethylchlorosilane was added dropwise over a 30-minute period. The mixture was then heated in a distillation apparatus with continuous reflux for a period of 30 minutes. The resultant mixture was cooled and then filtered.

Workup

  1. additionwas added dropwise over a 30-minute period
  2. temperatureThe mixture was then heated in a distillation apparatus
  3. temperaturewith continuous reflux for a period of 30 minutes
  4. filtrationfiltered

Sources & evidence

ORD record
ord-fbe78ec4353444bb8d533d07acd64de4
Source dataset
uspto-grants-1988_04
Patent number
US04736046

Reaction notes

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