Chloroform → HCID 14100538, compound

HRID 649286Notes

Reaction equation

Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[C:4]([Cl:10])[N:3]=1.CN1CCCC1.[CH:17](Cl)([Cl:19])[Cl:18].[OH-].[Na+]>>[Cl:8][C:7]1[C:2]([CH:17]([Cl:19])[Cl:18])=[N:3][C:4]([Cl:10])=[C:5]([Cl:9])[CH:6]=1

Participants

Reactant 4

HCID 6212Chloroform

HCID 84541-Methylpyrrolidine

HCID 14798Sodium Hydroxide

HCID 169902,3,5,6-Tetrachloropyridine

Product 1

HCID 14100538HCID 14100538, compound

Procedure

2,3,5,6-Tetrachloropyridine (1.1 g, 0.005 mole) was combined with 5 ml of N-methylpyrrolidine and 5 ml (about 0.062 mole) of chloroform in a reaction vessel and to the resulting solution 6 g of 50 percent aqueous sodium hydroxide (0.075 mole) was added with stirring. After 30 minutes the title compound was shown to be present in the reaction mixture by gas chromatography at approximately 15 percent conversion.

Workup

additionwas added

Sources & evidence

ORD record: ord-79a2935788e74628afae76e9eb50f957
Source dataset: uspto-grants-1988_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04739070

Reaction notes

Loading…