反应详情

Into a 25 mm micro flask equipped with spin bar, hot plate (having built in magnetic stirrer), reflux condenser and thermometer are placed 5 grams (0.0284 moles) of methyl-4-(propylthio)butyrate; 8.4 grams (0.1136 moles) of isobutanol and 0.05 grams of para-toluene sulfonic acid. The reaction mass is heated to reflux and maintained at reflux with stirring for a period of 14.5 hours. At the end of the refluxing, the reaction mass is cooled and distilled on a micro Vigreux column yielding the following fractions:

1. customInto a 25 mm micro flask equipped with spin bar
2. temperaturehot plate (having built in magnetic stirrer), reflux condenser
3. temperatureThe reaction mass is heated
4. temperatureto reflux
5. temperaturemaintained
6. temperatureat reflux
7. temperatureAt the end of the refluxing, the reaction mass is cooled
8. distillationdistilled on a micro Vigreux column
9. customyielding the following fractions