1-Chloro-2-nitrobenzene → HCID 18422279, compound

HRID 649946Notes

Reaction equation

HRID 649946 reaction equation
[NH2:1][C:2]1[S:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([CH3:11])[C:4]=2[C:3]=1[C:12]#[N:13].Cl[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N+:21]([O-:23])=[O:22]>CS(C)=O>[CH3:11][C:10]1[C:4]2[C:3]([C:12]#[N:13])=[C:2]([NH:1][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[N+:21]([O-:23])=[O:22])[S:6][C:5]=2[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 69451-Chloro-2-nitrobenzeneHCID 18422225221061-12-7

Product 1

HCID 18422279HCID 18422279, compoundYield 92.9%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

In the same manner as in Starting Material Synthesis Example 51 and using 2-amino-4-methylbenzo[b]thiophene-3-carbonitrile (3.8 g), 2-chloronitrobenzene(3.5 g) and dimethyl sulfoxide (45 ml), 4-methyl-2-(2-nitroanilino)benzo[b]thiophene-3-carbonitrile (5.8 g) was obtained.

Workup

  1. customMaterial Synthesis Example 51

Sources & evidence

ORD record
ord-c6110a5ec63f41d3970338b0bb548167
Source dataset
uspto-grants-2001_08
Patent number
US06271225B1

Reaction notes

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