Tert-Butylamine → N-tert-butylnaphthalene-2-carboxamide

HRID 650112Notes

Reaction equation

HRID 650112 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11](Cl)=[O:12].[C:14]([NH2:18])([CH3:17])([CH3:16])[CH3:15]>C(OCC)(=O)C>[C:14]([NH:18][C:11]([C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)=[O:12])([CH3:17])([CH3:16])[CH3:15]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 752462-Naphthoyl chloride

Product 1

HCID 667724N-tert-butylnaphthalene-2-carboxamide

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Following the procedure of Example 1 above and using 2-naphthoyl chloride and tert-butylamine (and ethyl acetate in place of benzene), the title compound was prepared as a white solid, m.p. 154.8-159.2° C.

Sources & evidence

ORD record
ord-4553dcf858f84f26beb39e78d9848d16
Source dataset
uspto-grants-2001_08
Patent number
US06271265B1

Reaction notes

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