1,2-Dichloroethane → Benzophenone

HRID 650514Notes

Reaction equation

HRID 650514 reaction equation
Cl[CH2:2][CH2:3]Cl.ClCCl.[C:8](#N)C.[CH:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH2:17]1[CH2:21][O:20][CH2:19][CH2:18]1>N1C=CC=CC=1>[C:19]([C:18]1[CH:17]=[CH:21][CH:3]=[CH:2][CH:8]=1)(=[O:20])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

7

Reactant 5

HCID 111,2-DichloroethaneHCID 241BenzeneHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 8028Tetrahydrofuran

Product 1

HCID 3102Benzophenone

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Melting points were determined on a Mel-temp II laboratory device and are uncorrected. NMR spectra were recorded on a Bruker 250 or Brucker 400 Fourier transform spectrometer; chemical shifts are reported in parts per million(δ), and signals are quoted as s (singlet), d (doublet), t (triplet), q (quartet), m (multiplet), and dd (doublet of doublets). UV spectra were obtained on a Beckman DU-7 spectrophotometer. Optical rotations were measured on a JASCO DIP-370 digital polarimeter. TLC was performed on Uniplates(silica gel) purchased from Analtech Co. Elemental analyses were performed by Atlantic Microlab, Inc, Norcross, Ga. Dry 1,2-dichloroethane, dichloromethane, acetonitrile, benzene and pyridine were obtained by distillation from CaH2 prior to use. Dry THF was obtained by distillation from Na and benzophenone when the solution became purple.

Workup

  1. customUV spectra were obtained on a Beckman DU-7 spectrophotometer

Sources & evidence

ORD record
ord-7fffafcb14ae4cd493ee6519bc731f78
Source dataset
uspto-grants-2001_08
Patent number
US06274589B1

Reaction notes

Loading…