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HRID65064

反应详情

EQUATION

反应方程式

HRID 65064 的结构方程式

REACTANTS

反应物

4
结构：CI
HCID6328

Methyl iodide

CH3I

结构：S=C=S
HCID6348

Carbon disulfide

CS2

结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：OC[C@@H]1Cc2c([nH]c3ccccc23)[C@H](c2ccccc2)N1
HCID86741014

rel-(1R,3R)-2,3,4,9-Tetrahydro-1-phenyl-1H-pyrido[3,4-b]indole-3-methanol

C18H18N2O

PRODUCTS

生成物

1
结构：CSC(=S)N1[C@H](CO)Cc2c([nH]c3ccccc23)[C@@H]1c1ccccc1
HCID86741013

未命名化合物

收率 78.1%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

In the same manner as described in Example 13 by using (1RS, 3RS)-cis-3-hydroxymethyl-1-phenyl-1,2,3,4-tetrahydro-β-carboline (300 mg) [J.A.C.S., 102, 6976 (1980)], triethylamine (220 mg), CS2 (160 mg), methyl iodide (306 mg) and dimethylsulfoxide (6 ml), there is prepared the title compound (310 mg, 78%) as white powder.