反应详情

In the same manner as described in Example 13 by using (3R)-3-(2-hydroxyethyl)-1,2,3,4-tetrahydro-β-carboline (100 mg), 2N NaOH (0.23 ml), CS2 (0.028 ml), 4-chlorobenzyl chloride (82 mg) and 70% ethanol (2.5 ml), there is prepared the title compound (66 mg, 34%) as white powder, [α]D20 -115.8° (c=1.0, ethyl acetate). Mass m/e: 416 (M+), 258 (M+ --p--Cl--C6H4 --CH2SH).