HCID 21709913, compound → HCID 21709932, compound

HRID 650869Notes

Reaction equation

HRID 650869 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[O:13])[N:11]=[N:10][NH:9]1.[CH3:14][N:15]([CH:19]1[CH2:24][CH2:23][S:22][CH2:21][CH2:20]1)[C:16](Cl)=[O:17]>CN(C)C1C=CN=CC=1>[CH3:14][N:15]([CH:19]1[CH2:24][CH2:23][S:22][CH2:21][CH2:20]1)[C:16]([N:11]1[C:12](=[O:13])[N:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Br:1])[N:9]=[N:10]1)=[O:17]

Participants

4

Reactant 2

HCID 21709913HCID 21709913, compoundHCID 178518971HCID 178518971, compound

Product 1

HCID 21709932HCID 21709932, compound

Reagents, catalysts & solvents 1

HCID 142844-(Dimethylamino)pyridineCatalyst

Procedure

Similarly to the process described in Example 1, 2.5 g (10 mmol) of 1-(2-bromophenyl)-1,2-dihydro-5H-tetrazol-5-one, 2 g (10 mmol) of N-methyl-N-(tetrahydro-2H-thiopyran-4-yl)carbamoyl chloride and 1.5 g (12 mmol) of 4-dimethylaminopyridine were reacted. Yield 2.5 g.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7b40b2bb5e034993b8a28ed5d0d229af
Source dataset
uspto-grants-2001_08
Patent number
US06277790B1

Reaction notes

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