Chloride → 4-Methoxy-3-(trifluoromethyl)benzoyl chloride

HRID 650957Notes

Reaction equation

HRID 650957 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1[C:12]([F:15])([F:14])[F:13].[Cl-:16].CN(C=O)C>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:16])=[O:8])=[CH:5][C:4]=1[C:12]([F:15])([F:14])[F:13]

Participants

5

Reactant 3

HCID 312ChlorideHCID 6228DimethylformamideHCID 27752954-Methoxy-3-(trifluoromethyl)benzoic acid

Product 1

HCID 27752984-Methoxy-3-(trifluoromethyl)benzoyl chloride

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from 4-methoxy-3-trifluoromethylbenzoic acid with oxalkyl chloride and DMF in chloroform at room temperature followed by evaporation in vacua.

Workup

  1. customfollowed by evaporation in vacua

Sources & evidence

ORD record
ord-13a5beb60f624fdc98a3a45284514b0a
Source dataset
uspto-grants-2001_08
Patent number
US06277861B1

Reaction notes

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