反应详情

Quantities: 4-bromo-4′-hydroxybiphenyl (67) (20.00 g, 0.08 mol), 1-bromodecane (22.12 g, 0.10 mol), anhydrous potassium carbonate (57.10 g, 0.413 mol), potassium iodide (trace), butanone (500 ml). The experimental procedure was as described for the preparation of compound 57. The cooled mixture of product and inorganic salts was filtered off and washed carefully with dilute hydrochloric acid to remove the potassium carbonate. The white product was then washed with water until acid-free and heated under reflux with a minimum volume of ethanol to remove traces of 1-bromodecane. The product was filtered off, washed with cold ethanol and dried in vacuo to yield colourless crystals.

1. additionThe cooled mixture of product and inorganic salts
2. filtrationwas filtered off
3. washwashed carefully with dilute hydrochloric acid
4. customto remove the potassium carbonate
5. washThe white product was then washed with water until acid-free and
6. temperatureheated
7. temperatureunder reflux with a minimum volume of ethanol
8. customto remove traces of 1-bromodecane
9. filtrationThe product was filtered off
10. washwashed with cold ethanol
11. customdried in vacuo
12. customto yield colourless crystals