反应详情

A mixture of 2.2 g. of methyl 4-[14-(trimethylsilyl)tetradecylamino]benzoate, 280 mg. of 1,3-propanediol and 1.37 g. of p-toluenesulfonic acid is heated at 180° C. for 18 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield the product as a white solid.

1. additionA mixture of 2.2 g
2. customis partitioned between ether and 3% aqueous sodium carbonate solution
3. customThe ether layer is separated
4. customdried
5. customevaporated