Hydrochloric Acid → HCID 13369493, compound

HRID 652296Notes

Reaction equation

HRID 652296 reaction equation
[CH:1]([NH:4][C:5](=O)[CH:6]([Cl:8])[Cl:7])([CH3:3])[CH3:2].Cl.P(Cl)(Cl)([Cl:13])=O>P(Cl)(Cl)(Cl)(Cl)Cl>[CH:1]([N:4]=[C:5]([Cl:13])[CH:6]([Cl:8])[Cl:7])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 24813Phosphorus oxychlorideHCID 3550524HCID 3550524, compound

Product 1

HCID 13369493HCID 13369493, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 24819Phosphorus pentachlorideSolvent

Procedure

N-isopropyldichloroacetamide, 249.5 grams (2.94 mole), and 210 milliliters of phosphorous pentachloride, 306.5 grams (2.94 mole), was added and the mixture was stirred vigorously and heated at reflux until hydrogen chloride evolution ceased. The phosphorous oxychloride was stripped off at reduced pressure. Distillation at 4.5 millimeters gave 360 grams (65% yield) of N-isopropyldichloroacetimidoyl chloride, b.p. 63°-72° C.

Workup

  1. temperatureheated
  2. distillationDistillation at 4.5 millimeters

Sources & evidence

ORD record
ord-5259c0aa697a4eb4be3304ca4856ef4c
Source dataset
uspto-grants-1987_06
Patent number
US04670593

Reaction notes

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