4-Hydroxybenzaldehyde → HCID 185042, compound

HRID 652568Notes

Reaction equation

HRID 652568 reaction equation
[NH2:1]CCC(O)=O.[OH:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=O.[NH2:16][CH2:17][C:18]([OH:20])=O.OC1C=CC([CH:26]=[O:27])=CC=1>>[OH:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=[C:17]1[NH:16][C:26](=[O:27])[NH:1][C:18]1=[O:20]

Participants

5

Reactant 4

HCID 1264-HydroxybenzaldehydeHCID 239Beta-AlanineHCID 750GlycineHCID 6998Salicylaldehyde

Product 1

HCID 185042HCID 185042, compound

Procedure

5-(o-Hydroxybenzylidene)-hydantoin was prepared in the same manner as in Example 4, except that 22.2 g (0.25 mol) of β-alanine and 61.1 g (0.50 mol) of o-hydroxybenzaldehyde were used in lieu of glycine and p-hydroxybenzaldehyde, respectively, and that the reaction time was 6 hours. During the reaction, the pH of the reaction mixture was 9.6 to 9.2.

Workup

  1. customDuring the reaction

Sources & evidence

ORD record
ord-efa99f47a74542d89ac242a2ce4e1cd3
Source dataset
uspto-grants-1987_06
Patent number
US04672127

Reaction notes

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