反应详情

A solution of ε(4-nitro 2-methoxy-benzenesulfonamido)caproic acid (1.4 g) in solution in ethyl acetate (150 cm3) is stirred magnetically under a hydrogen atmosphere in the presence of 5% palladized charcoal (120 mg). After four hours, the hydrogen absorption being terminated, the catalyst is filtered and the filtrate concentrated under reduced pressure. Pure ε(4-amino 2-methoxy-benzenesulfonamido)caproic acid is obtained, with a yield of 98%.

1. customthe hydrogen absorption
2. custombeing terminated
3. filtrationthe catalyst is filtered
4. concentrationthe filtrate concentrated under reduced pressure