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HRID652757

反应详情

EQUATION

反应方程式

HRID 652757 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

2 次

结构：COc1c(C(C)C)cc(S(N)(=O)=O)c(C)c1C(=O)O
HCID20196838

未命名化合物

PRODUCTS

生成物

1
结构：COc1c(C(C)C)cc(S(N)(=O)=O)c(C)c1C(=O)Cl
HCID20196820

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CN(C)C=O
催化剂HCID6228

N,N-Dimethylformamide

C3H7NO

结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

72 g of 2-methoxy-3-isopropyl-5-sulphamoyl-6-methylbenzoic acid (0.25 mole), 250 ml of chloroform, 23 ml of thionyl chloride and 3 drops of dimethylformamide are placed in a 1 liter flask fitted with an agitator and a condenser. The mixture is heated to reflux for 1.5 hours, then 18 ml of thionyl chloride is added and the reflux is continued for 1.5 hours. The solids dissolve completely.

WORKUP

后处理

  1. customfitted with an agitator and a condenser
  2. temperatureThe mixture is heated
  3. temperatureto reflux for 1.5 hours
  4. dissolutionThe solids dissolve completely