Potassium Iodide → HCID 20195590, compound

HRID 653085Notes

Reaction equation

HRID 653085 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][O:14][CH3:15].[I-:16].[K+].[C:18]1([P:24]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(#N)C>[I-:16].[CH3:15][O:14][CH2:13][CH2:12][O:11][CH2:10][CH2:9][O:8][CH2:7][CH2:6][O:5][CH2:4][CH2:3][CH2:2][P+:24]([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 11776TriphenylphosphineHCID 13688963HCID 13688963, compound

Product 1

HCID 20195590HCID 20195590, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
-20 °C

Procedure

To a solution of 1-chloro-3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}propane (2.4 g) in dry acetonitrile (30 ml) was added potassium iodide (1.66 g), and triphenylphosphine (2.63 g) and the suspension heated at reflux for 24 hours. The cooled solution was filtered and the filtrate evaporated under reduced pressure to give a colourless oil which on cooling to -20° C. gave a white oily solid.

Workup

  1. temperaturethe suspension heated
  2. temperatureat reflux for 24 hours
  3. filtrationThe cooled solution was filtered
  4. customthe filtrate evaporated under reduced pressure
  5. customto give a colourless oil which
  6. customgave a white oily solid

Sources & evidence

ORD record
ord-c5c2d42cb66c4e179c8c8cddfdd0f993
Source dataset
uspto-grants-1987_06
Patent number
US04675335

Reaction notes

Loading…