HRID653639

反应详情

EQUATION

反应方程式

HRID 653639 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

CONDITIONS

反应条件

温度
80 °C

PROCEDURE

实验过程

A mixture of 29.75 g (0.168 mol) of the product of Step A, CHCl3 (25 mL) and POCl3 (160 mL) was heated to 80° C. for 1 hour. After pouring over ice, the mixture was neutralized by careful addition of NH4OH and extracted with EtOAc. Concentration gave the title compound as a solid.

WORKUP

后处理

  1. additionAfter pouring over ice
  2. extractionextracted with EtOAc
  3. concentrationConcentration