Trifluoroacetic acid → HCID 131717452, compound

HRID 653860Notes

Reaction equation

HRID 653860 reaction equation
[CH:1]([NH:3][C@@H:4]1[C:34](=[O:35])[N:6]2[C:7]([C:22]([O:24]CC3C=CC(OC)=CC=3)=[O:23])=[C:8](/[CH:11]=[CH:12]/[CH2:13][N+:14]([CH2:18][C:19](=[O:21])[NH2:20])([CH2:16][CH3:17])[CH3:15])[CH2:9][S:10][C@H:5]12)=[O:2].[I-].[F:37][C:38]([F:43])([F:42])[C:39]([OH:41])=[O:40]>C1(OC)C=CC=CC=1>[F:37][C:38]([F:43])([F:42])[C:39]([O-:41])=[O:40].[CH:1]([NH:3][C@@H:4]1[C:34](=[O:35])[N:6]2[C:7]([C:22]([OH:24])=[O:23])=[C:8](/[CH:11]=[CH:12]/[CH2:13][N+:14]([CH2:18][C:19](=[O:21])[NH2:20])([CH2:16][CH3:17])[CH3:15])[CH2:9][S:10][C@H:5]12)=[O:2]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 131717453HCID 131717453, compound

Product 1

HCID 131717452HCID 131717452, compound

Reagents, catalysts & solvents 1

HCID 7519AnisoleSolvent

Procedure

In a similar manner as in Example 5, the compound (3.4 g) of Example 25 was suspended in anisole (20 ml), followed by an addition of trifluoroacetic acid (23 ml) to obtain the target compound (2.04 g).

Sources & evidence

ORD record
ord-64a4f8d9a38f49438c38acbacf0fa5a3
Source dataset
uspto-grants-1992_07
Patent number
US05128465

Reaction notes

Loading…