Hydroxyamine hydrochloride → HCID 15718589, compound

HRID 654228Notes

Reaction equation

HRID 654228 reaction equation
[CH:1]([CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[O:13][CH3:14])[C:4]1=[O:15])=O.Cl.[NH2:17]O>CO>[CH3:14][O:13][C:9]1[CH:8]=[CH:7][CH:6]=[C:5]2[C:10]=1[CH2:11][CH2:12][C:3]1[CH:1]=[N:17][O:15][C:4]=12

Participants

4

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 15718588HCID 15718588, compound

Product 1

HCID 15718589HCID 15718589, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of the product obtained in step (i) (23.8 g, 0.11 mol) and hydroxylamine hydrochloride (8.2 g, 0.12 mol) in methanol (300 ml) is refluxed for ten minutes and then evaporated off under vacuum. Water is added thereto and the mixture is extracted with ethyl ether affording 19 g of the compound indicated in the title; m.p. 84°-86° C.

Workup

  1. temperatureis refluxed for ten minutes
  2. customevaporated off under vacuum
  3. additionWater is added
  4. extractionthe mixture is extracted with ethyl ether affording 19 g of the compound

Sources & evidence

ORD record
ord-fa46b724462049768430a5f824b7c26d
Source dataset
uspto-grants-1992_07
Patent number
US05130339

Reaction notes

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