反应详情

温度

20 °C

20.0 g (71 mmol) of 2-amino-4-trichloromethyl-6-trifluoromethyl-1,3,5-triazine were added at 22° C. to a solution of 0.48 g (7.1 mmol) of sodium ethanolate in 100 ml of ethanol. The pale yellowish green solution was then refluxed for 30 minutes and, after cooling to 20° C., 20 ml of water were added and the mixture was neutralized with 2 normal hydrochloric acid. After this, most of the solvent was removed at 40° C. under reduced pressure, adding 100 ml of water a little at a time so that the solid did not agglomerate. The product was isolated in a similar manner to Example 2.

1. temperatureThe pale yellowish green solution was then refluxed for 30 minutes
2. customAfter this, most of the solvent was removed at 40° C. under reduced pressure
3. additionadding 100 ml of water a little at a time so that the solid
4. customThe product was isolated in a similar manner to Example 2