hydroxylamine-O-sulfonic acid → HCID 19774693, compound

HRID 654293Notes

Reaction equation

HRID 654293 reaction equation
[CH:1]([CH:3]1[CH2:8][C:7](=[O:9])[CH:6]([C:10](=[O:12])[CH3:11])[C:5](=[O:13])[CH2:4]1)=O.[NH2:14]OS(O)(=O)=O>O>[O:13]=[C:5]1[CH:6]([C:10](=[O:12])[CH3:11])[C:7](=[O:9])[CH2:8][CH:3]([C:1]#[N:14])[CH2:4]1

Participants

4

Reactant 2

HCID 76284hydroxylamine-O-sulfonic acidHCID 15003566HCID 15003566, compound

Product 1

HCID 19774693HCID 19774693, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

19.3 g (0.11 mol) of 5-formyl-2-acetylcyclohexane-1,3-dione were introduced into 200 ml of distilled water and, at room temperature, 14.7 g (0.13 mol) of hydroxylamine-O-sulfonic acid were added. The mixture was then stirred at room temperature for 17 h. The precipitate was filtered off with suction, washed with water and dried. 11.5 g (61% of theory) of 3,5-dioxo-4-acetylcyclohexanecarbonitrile were obtained (melting point 94 to 97° C.).

Workup

  1. filtrationThe precipitate was filtered off with suction
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-7f6ddd33b16841bdad28181cb623bc6a
Source dataset
uspto-grants-1992_07
Patent number
US05130453

Reaction notes

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