Sodium Thiosulfate → HCID 14986469, compound

HRID 654702Notes

Reaction equation

HRID 654702 reaction equation
C([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9](C=O)=[CH:8][C:7]([O:15][CH3:16])=[CH:6]2)C.Cl[C:18]1C=CC=C(C(OO)=O)[CH:19]=1.S([O-])([O-])(=[O:30])=S.[Na+].[Na+]>ClCCl>[CH2:18]([C:12]1[CH:11]=[C:10]2[C:5](=[CH:4][CH:3]=1)[C:6]([OH:30])=[C:7]([O:15][CH3:16])[CH:8]=[CH:9]2)[CH3:19]

Participants

5

Reactant 3

HCID 24477Sodium ThiosulfateHCID 70297m-Chloroperbenzoic acidHCID 53997382HCID 53997382, compound

Product 1

HCID 14986469HCID 14986469, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
0 °C

Procedure

4.4 g of 6-ethyl-3-methoxy-1-naphthalene carbaldehyde and 4.9 g of 80-85% m-chloroperbenzoic acid were dissolved in 40 ml of dichloromethane and then refluxed under heating for 30 min. The solution was cooled to 0° C. and after adding an aqueous saturated solution of sodium thiosulfate and stirring for 20 min, insoluble matters were removed by filtration and then the filtrate was extracted with ethyl acetate. The extract was washed with a saturated aqueous solution of sodium chloride and then dried over anhydrous magnesium sulfate.

Workup

  1. temperaturerefluxed
  2. temperatureunder heating for 30 min
  3. custominsoluble matters were removed by filtration
  4. extractionthe filtrate was extracted with ethyl acetate
  5. washThe extract was washed with a saturated aqueous solution of sodium chloride
  6. dry with materialdried over anhydrous magnesium sulfate

Sources & evidence

ORD record
ord-19b132a532d94e24a3d56d5a37e82094
Source dataset
uspto-grants-1992_07
Patent number
US05134111

Reaction notes

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