Iodoethane → HCID 15724563, compound

HRID 654834Notes

Reaction equation

HRID 654834 reaction equation
[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=1)[C:5]([O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[O:6])(=[O:3])[CH3:2].[CH2:39]([I:41])[CH3:40]>C(#N)C>[I-:41].[C:1]([N:4]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N+:34]=1[CH2:39][CH3:40])[C:5]([O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[O:6])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 6340IodoethaneHCID 19886466HCID 19886466, compound

Product 1

HCID 15724563HCID 15724563, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of the compound obtained in example 2 (692 mg, 1.29 mmol) in acetonitrile (1 mL) and ethyl iodide (1 mL) was heated at 70° C. for three days. The solution was concentrated in vacuo, the residue was dissolved in dichloromethane and precipitated with ether. The solid was filtered and dried to yield the desired compound as a yellowish powder (693 mg, 77%).

Workup

  1. concentrationThe solution was concentrated in vacuo
  2. dissolutionthe residue was dissolved in dichloromethane
  3. customprecipitated with ether
  4. filtrationThe solid was filtered
  5. customdried

Sources & evidence

ORD record
ord-de08f72d907245d19f2b10ea1b8a6e86
Source dataset
uspto-grants-1992_07
Patent number
US05134151

Reaction notes

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