反应详情

1.5 g 2-benzoyl-pyridine N-oxide (T. Kato et. al., see reference in Ex. 11) and 3.6 ml POCl3 are refluxed for 25 minutes. The cooled mixture is added to slightly alkaline ice:water, extracted with chloroform, the organic extract dried and solvent removed in vacuo. Yield: 1.1 g of title product, which by thin layer and gas chromatography is identical with that described in Ex. 7.

1. additionThe cooled mixture is added to slightly alkaline ice
2. extractionwater, extracted with chloroform
3. extractionthe organic extract
4. customdried
5. customsolvent removed in vacuo