反应详情

A solution of 6.0 g (0.06 mole) of tetrahydro-4H-pyran-4-one, 21.6 g (0.13 mole) of 2,3-dimethyl-p-anisaldehyde in 75 ml of EtOH and 10 ml of concentrated HCl is stirred and heated at reflux for 3 hours. The product gradually precipitates during this period. After cooling, this material is filtered and treated with ether to give 9.1 g (39%) of yellow crystals, m.p. 225°-227°.

1. temperatureheated
2. temperatureat reflux for 3 hours
3. customThe product gradually precipitates during this period
4. temperatureAfter cooling
5. filtrationthis material is filtered
6. additiontreated with ether