反应详情

A mixture of 4,5-difluoro-1,2-benzenediamine (0.60 g) and 50% ethyl glyoxalate in toluene (0.87 ml) in ethanol (25 ml) was heated under reflux for 2 hours then cooled. After refrigeration overnight, the resulting solid was collected and washed with ice-cold ethanol and dried under vacuum to give a solid (0.57 g; 75%).

1. temperaturewas heated
2. temperatureunder reflux for 2 hours
3. temperaturethen cooled
4. customthe resulting solid was collected
5. washwashed with ice-cold ethanol
6. customdried under vacuum
7. customto give a solid (0.57 g; 75%)