Sodium Chloride → HCID 86594595, compound

HRID 657450Notes

Reaction equation

HRID 657450 reaction equation
[CH3:1][C:2]([CH3:14])([C:10]([CH3:13])=[CH:11][CH3:12])[CH2:3][CH2:4]/[CH:5]=[CH:6]/[C:7]([OH:9])=O.ClC(OCC)=O.[CH2:21]([N:23](CC)CC)[CH3:22].C(N)C.[Cl-].[Na+]>C1COCC1>[CH2:21]([NH:23][C:7](=[O:9])/[CH:6]=[CH:5]/[CH2:4][CH2:3][C:2]([CH3:1])([CH3:14])[C:10]([CH3:13])=[CH:11][CH3:12])[CH3:22]

Participants

7

Reactant 5

HCID 5234Sodium ChlorideHCID 6341EthylamineHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 86594596HCID 86594596, compound

Product 1

HCID 86594595HCID 86594595, compoundYield 22%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

4-(2,2,3-Trimethyl-3-penten-1-yl)-2E-butenoic acid 1 eq, ethyl chloroformate 1.5 eq, triethylamine 1.5 eq, ethylamine 1.5 eq as a 2.0M solution in THF, quench with 10% sodium chloride solution, yield=22%.

Sources & evidence

ORD record
ord-271e967de5dc488f957812cfa7465ab1
Source dataset
uspto-grants-2011_12
Patent number
US08075937B2

Reaction notes

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