Dimethylcarbamoyl Chloride → HCID 68973954, compound

HRID 657569Notes

Reaction equation

Cl.CN(C)C(=O)O[C:6]1[CH:7]=[C:8]2[C:11](=[CH:12][CH:13]=1)[CH:10]([CH2:14][NH:15][CH2:16][CH2:17][C:18]([N:20]1[CH2:26][CH2:25][C:24]3[CH:27]=[C:28]([O:33][CH3:34])[C:29]([O:31][CH3:32])=[CH:30][C:23]=3[CH2:22][CH2:21]1)=[O:19])[CH2:9]2.CN(C)C([Cl:41])=[O:40].[CH2:43]([N:45]([CH2:49][CH3:50])[C:46](Cl)=[O:47])[CH3:44]>>[ClH:41].[CH2:43]([N:45]([CH2:49][CH3:50])[C:46](=[O:40])[O:47][C:6]1[CH:7]=[C:8]2[C:11](=[CH:12][CH:13]=1)[CH:10]([CH2:14][NH:15][CH2:16][CH2:17][C:18]([N:20]1[CH2:21][CH2:22][C:23]3[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[CH:27][C:24]=3[CH2:25][CH2:26]1)=[O:19])[CH2:9]2)[CH3:44]

Participants

Reactant 3

HCID 6598Dimethylcarbamoyl Chloride

HCID 6916Diethylcarbamoyl chloride

HCID 68973645HCID 68973645, compound

Product 1

HCID 68973954HCID 68973954, compound

Procedure

The same procedure is used as for the compound of Example 54, but with replacement, in Step 1, of the N,N-dimethylcarbamoyl chloride by N,N-diethylcarbamoyl chloride.

Sources & evidence

ORD record: ord-d5659b6534a242f0becdfd04e0ece8a6
Source dataset: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08076325B2

Reaction notes

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