反应详情

A mixture of 2 g of 1,3-dimethyl-6-hydroxyaminouracil, 20 ml of dimethylformamide and 20 ml of ethyl orthoformate is boiled at 160° C. for 1 hour, after which the solvent is distilled off. To the residue is added ethanol and the resultant crystals are collected by filtration. As recrystallized from hot water, 1.0 g of the captioned compound is obtained as colorless prisms, melting point: 170°-171° C.

1. customfor 1 hour
2. distillationafter which the solvent is distilled off
3. additionTo the residue is added ethanol
4. filtrationthe resultant crystals are collected by filtration
5. customAs recrystallized from hot water