反应详情

温度

150 °C

A suspension of 4-methoxybenzene-1,2-diamine dihydrochloride in diethyl oxalate (8 eq) was treated with Et3N (2 eq) and then heated at 150° C. for 2 h. The mixture was cooled and filtered, and then the collected solid was washed with H2O and EtOH. The residue was dried to give the title compound (69%). MS (ES+) m/z 193 (M+H)+

1. temperatureThe mixture was cooled
2. filtrationfiltered
3. washthe collected solid was washed with H2O and EtOH
4. customThe residue was dried