反应详情

A mixture of (Z) -4-(3-benzyloxy-4-nitrophenyl)-3-phenyl-but-3-en-2-one (760 mg, 2.03 mmol), 5% platinum on carbon (114 mg) in EtOAc (10 mL) is hydrogenated at 1 atm for 18 h. The mixture is filtered through Celite, washed with EtOAc and the filtrate is concentrated. The residue is purified by flash chromatography using methylene chloride/MeOH (100:1) as eluent to give the title compound as a yellow solid.

1. filtrationThe mixture is filtered through Celite
2. washwashed with EtOAc
3. concentrationthe filtrate is concentrated
4. customThe residue is purified by flash chromatography