反应详情

To a stirred solution of benzyl bromide (6.9 g, 40.3 mmol) and 3-hydroxy-4-nitrobenzaldehyde (9.7 g, 58.0 mmol) is added potassium carbonate (8.9 g, 64.4 mmol). The mixture is stirred at RT for 18 h, diluted with water and extracted with EtOAc. The organic phase is washed with aqueous potassium carbonate and brine, dried over MgSO4, filtered and concentrated to afford the title compound as a yellow solid: (M+1)+=258.

1. extractionextracted with EtOAc
2. washThe organic phase is washed with aqueous potassium carbonate and brine
3. dry with materialdried over MgSO4
4. filtrationfiltered
5. concentrationconcentrated