反应详情

To a solution of 7-(3-benzyloxy-4-nitrobenzyl)-azepan-2-one (600 mg, 1.7 mmol) in EtOAc (20 mL) is added tin (II) chloride dihydrate. The mixture is stirred at RT for 18 h then water is added. The mixture is extracted with EtOAc and the organic phase is washed with water and brine. The solution is dried over sodium sulfate and the solvent removed under reduced pressure to give the title compound: (M+1)+=325.

1. extractionThe mixture is extracted with EtOAc
2. washthe organic phase is washed with water and brine
3. dry with materialThe solution is dried over sodium sulfate
4. customthe solvent removed under reduced pressure