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HRID661346

反应详情

EQUATION

反应方程式

HRID 661346 的结构方程式

REACTANTS

反应物

3
结构：BrCc1ccccc1Br
HCID76965

2-Bromobenzyl bromide

C7H6Br2

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CCOC(=O)c1ccc(N2CCNCC2)cc1
HCID2761178

ethyl 4-(piperazin-1-yl)benzoate

C13H18N2O2

PRODUCTS

生成物

1
结构：CCOC(=O)c1ccc(N2CCN(Cc3ccccc3Br)CC2)cc1
HCID16109102

Ethyl 4-{4-[(2-bromophenyl)methyl]piperazin-1-yl}benzoate

C20H23BrN2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

A mixture of EXAMPLE 1A (23.43 g), 2-bromobenzyl bromide (26.24 g), and DIEA (20.94 mL) in acetonitrile (200 mL) at 25° C. was stirred for 2 hours and filtered.

WORKUP

后处理

  1. filtrationfiltered