反应详情

A mixture of 4,7-dihydro-4,7-dioxo-6-hydroxy-1H-cyclohepta[b]pyridine-2-carboxylic acid ethyl ester (2.5 g, described in Example 3) and 19% hydrochloric acid (75 ml) is refluxed for 1 hour and cooled to room temperature. The crystalline precipitate is collected and washed with water, ethanol and ether to obtain the title compound, mp > 270° C.

1. temperatureis refluxed for 1 hour
2. customThe crystalline precipitate is collected
3. washwashed with water, ethanol and ether